Evidence of early defects in Cajal Retzius cell localisation during brain development in a mouse model of dystroglycanopathy
ConclusionsThese observations identify Cajal Retzius cell mislocalisation as an early event during the development of cortical defects thereby identifying an earlier onset and more complex pathogenesis than originally reported for the secondary dystroglycanopathies. Overall this study provides new insight into central nervous system involvement in this group of diseases.This article is protected by copyright. All rights reserved.
Source: Neuropathology and Applied Neurobiology - Category: Neurology Authors: H S Booler, V Pagalday ‐Vergara, J L Williams, M Hopkinson, S C Brown Tags: Original Article Source Type: research