L5: an LDL fraction in which pathogenic activity of LDL is concentrated

After the establishment of LDL as a risk factor for cardiovascular disease (CVD), researchers have been seeking the real nature of pathological LDL. L5, a good candidate to be it, is coming. In this issue of this journal, Akyol S et al. reviewed recent progress of the study of L5, a subfraction of LDL, in the pathogenesis of atherothrombotic diseases [1]. Here, I am summarizing points of the L5 study.

Source: Trends in Cardiovascular Medicine - December 21, 2016 Category: Cardiology Authors: Tatsuya Sawamura, Yoshiko Fujita, Sayaka Horiuchi, Akemi Kakino Source Type: research