microRNA-145 modulates epithelial-mesenchymal transition and suppresses proliferation, migration and invasion by targeting SIP1 in human cervical cancer cells

ConclusionOur data indicate that lowmiR-145 expression levels in conjunction with elevatedSIP1 expression levels may contribute to cervical cancer development.MiR-145-mediated regulation ofSIP1 provides a novel mechanistic basis for its tumour suppressive mode of action in human cervical cancer cells.

http://link.springer.com/10.1007/s13402-016-0307-3

Source: Cellular Oncology - December 7, 2016 Category: Cancer & Oncology Source Type: research