Nocturnal antihypertensive treatment in patients with type 1 diabetes with autonomic neuropathy and non-dipping: a randomised, placebo-controlled, double-blind cross-over trial
Conclusions
We demonstrated that patients with T1D with CAN and non-dipping can be treated with an ACE inhibitor at night as BD as opposed to MD increased BP dipping, thereby diminishing the abnormal BP profile. The potentially beneficial effect on long-term cardiovascular risk remains to be determined.
Trial registration number
EudraCT2012-002136-90; Post-results.
Source: BMJ Open - Category: Journals (General) Authors: Hjortkjaer, H. O., Jensen, T., Kofoed, K. F., Mogensen, U. M., Sigvardsen, P. E., Kober, L., Hilsted, K. L., Corinth, H., Theilade, S., Hilsted, J. Tags: Open access, Cardiovascular medicine, Diabetes and Endocrinology Research Source Type: research
More News: Cardiology | Cardiovascular | Diabetes | Diabetes Type 1 | Enalapril | Endocrinology | General Medicine | Heart | Neurology | Study