Update on the Preventive Antibiotics in Stroke Study (PASS): a randomised controlled phase 3 clinical trial

Conclusion:
The data from PASS will establish whether preventive antibiotic therapy in acute stroke improves functional outcome by preventing infection. In this update, we changed our primary outcome analysis from dichotomisation to ordinal regression analysis.Trial registration: Current controlled trials; ISRCTN66140176. Date of registration: 6 April 2010.

Source: Epidemiologic Perspectives and Innovations - April 21, 2014 Category: Epidemiology Authors: Willeke F WestendorpJan-Dirk VermeijNan van GelovenDiederik WJ DippelMarcel GW DijkgraafTom van der PollJan M PrinsLodewijk SpanjaardFrederique H VermeijPaul J NederkoornDiederik van de Beek Source Type: research