Evaluation of KIM-1 and NGAL as Early Indicators for Assessment of Gentamycin-Induced Nephrotoxicity < b > < i > In Vivo < /i > < /b > and < b > < i > In Vitro < /i > < /b >

Conclusions: In contrast, no significant increase in the expression of the biomarker genes and proteins were evident in HK-2 cells after treated by Gentamycin for up to 48h, suggesting that they may not be suitable endpoints for sensitive detection of nephrotoxic effects in vitro.Kidney Blood Press Res 2016;41:911-918
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research