Molecular drug susceptibility testing against the first-line (rifampin and isoniazid) and second-line (ciprofloxacin –amikacin and kanamycin) treatment in different subtypes of Mycobacterium simiae

Conclusion Regarding the given result, first-line tuberculosis drugs should be excluded from the treatment regimen of M. simiae patients. In addition, subtype I seems to be the most or even the only isolated M. simiae subtype among all Iranian patients. While both amikacin and kanamycin drugs showed better efficacy in the treatment M. simiae, the most susceptible antibiotic is still indeterminate.
Source: International Journal of Mycobacteriology - Category: Infectious Diseases Source Type: research