The Role of the Iron Stain in Assessing Intracranial Hemorrhage.

In conclusion, the Prussian Blue reaction was unreliable as an indicator of timing in intracranial hemorrhage. The use of the Prussian blue reaction as an independent indicator of chronicity is therefore not valid and can be misleading. Caution is indicated when employing iron staining for timing purposes, as its only use is to highlight, as opposed to identify, pre-existing lesions. With respect to brain lesions, the Prussian blue reaction should not be used in place of the clinical timing of the neurologic decline, or clinical data that is otherwise more accurate and less susceptible to false positive results. PMID: 27857815 [PubMed - in process]
Source: The Open Neurology Journal - Category: Neurology Tags: Open Neurol J Source Type: research