Genetics: Genetic factors in the regulation of blood pressure
Nature Reviews Nephrology 12, 716 (2016).
doi:10.1038/nrneph.2016.150
Authors: Nicholette D. Palmer & Barry I. Freedman
Three large-scale association studies provide insights into the genetic architecture of blood pressure regulation, identifying new common variants of modest effect and providing insights into the impact of rare and low-frequency variants. The findings suggest that newly identified variants act through indirect disease pathways and suggest targeting of causal networks might improve outcomes in patients with hypertension.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Nicholette D. Palmer Barry I. Freedman Tags: News and Views Source Type: research