High-sensitivity C-reactive protein in stroke patients – The importance in consideration of influence of multiple factors in the predictability for disease severity and death

Publication date: Available online 4 November 2016 Source:Journal of Clinical Neuroscience Author(s): Hong Yu, Yue Huang, XinYu Chen, WenBao Nie, YongJun Wang, Yan Jiao, Guy L. Reed, Weikuan Gu, Hong Chen High sensitivity C-reactive protein (hsCRP) has been evaluated as a biomarker in stroke and relevant pathological diseases. While its predictive values in several pathological phenotypes have been confirmed, controversy exists among different studies. This review summarizes reports of the predictive values of hsCRP for the diagnosis, etiology, prognosis and mortality of stroke diseases. The current literature suggests that CRP expression is influenced by multiple factors, such as polymorphisms, the genomic backgrounds and gender. However, few reported studies analyzed data based on all these multiple factors. Future studies should focus on comprehensive analysis based on multiple factors.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research