A Combination Trial of Estriol Plus Glatimer Acetate in Relapsing-Remitting Multiple Sclerosis (I7-2.002)

CONCLUSIONS: Effects of treatment of RRMS women with a dose of estriol to induce a pregnancy level in serum will be discussed in the context of future development of estriol as a novel treatment in MS, and insights in understanding disease protection during pregnancy will be explored.Disclosure: Dr. Voskuhl has received personal compensation for activities with Synthetic Biologics Inc. Dr. Voskuhl has received license fee payments from UCLA. Dr. Voskuhl has received research support from Synthetic Biologics, and Karo Bio. Dr. Wang has nothing to disclose. Dr. Wu has nothing to disclose. Dr. Sicotte has nothing to disclose. Dr. Bates has received personal compensation for activities with Teva Neuroscience, and Biogen Idec, Dr. Beaver has nothing to disclose. Dr. Corboy has received personal compensation for activities with ProCE as a speaker, and Celgene Therapeutics, Teva Neuroscience, and Novartis as a speaker. Dr. Corboy has received research support from Novartis, BioMS, Eli Lilly & Co., Celgene Therapeutics, and Immune Tolerance Network. Dr. Cross has received personal compensation for activities with Biogen Idec, Genzyme Corporation, GlaxoSmithKline, Inc., Hoffman-La Roche, Teva Neuroscience, Novartis, and Questcor. Dr. Cross has received research support from Hoffman-La Roche and Sanofi-Aventis Pharmaceuticals, Inc. Dr. Dhib-Jalbut has received personal compensation for activities with Serono and Novartis as a consultant. Dr. Ford has received personal compensation ...

Source: Neurology - April 9, 2014 Category: Neurology Authors: Voskuhl, R., Wang, H., Wu, T. C. J., Sicotte, N., Bates, A., Beaver, G., Corboy, J., Cross, A., Dhib-Jalbut, S., Ford, C., Giesser, B., Jacobs, D., Lynch, S., Pachner, A., Racke, M., Ratchford, J., Reder, A., Rose, J., Wingerchuk, D., Burnett, M., Tseng, Tags: Emerging Therapeutic Advances in Multiple Sclerosis Data Blitz Presentations Source Type: research