Gustatory Dysfunction in Multiple Sclerosis (P6.159)

CONCLUSIONS:MS was associated with taste dysfunction on both the front and back of the tongue in about one-fifth of the patients. Lesion activity, in some brain regions, was correlated with the magnitude of the deficits for some taste stimuli. Importantly, all classical taste qualities are affected, with a slightly greater influence on tastants that employ transduction mechanisms that directly gate membrane channel receptors.Study Supported by:NIH RO1 DC 02974, NIH R01 NS 37172, and DOD W81XWH-09-1-0467.Disclosure: Dr. Doty has received personal compensation for activities with Sensonics, Inc. Adams & Adams, Christopher Abdoney, Clancy & Stevens, Columbia University, Federal Defenders, Middle Dist. Alabama, Lathrop & Gage LLP, Merck, Murphy-Brown LLC, National Institutes of Health, Rothshild Wishek & Sands LLP, Pfizer, Inc, Sensonics, Inc., TASA Group, Western Medical Assessments, and Young, Conway, Stargatt & Taylor. Dr. Doty holds stock and/or stock options in Sensonics, Inc., which sponsored research in which Dr. Doty was involved as an investigator. Dr. Tourbier has nothing to disclose. Dr. Leon-Sarmiento has nothing to disclose. Dr. Udupa has nothing to disclose. Dr. Karacali has nothing to disclose. Dr. Moonis has nothing to disclose. Dr. Beals has nothing to disclose. Dr. Fabius has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Palecanda has nothing to disclose. Dr. Souza has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Multiple Sclerosis Symptoms and Comorbidities Source Type: research