Current Safety Concerns with Human Papillomavirus Vaccine: A Cluster Analysis of Reports in VigiBase ®

ConclusionsCluster analysis reveals additional reports of AEs following HPV vaccination that are serious in nature and describe symptoms that overlap those reported in cases from the recent safety signals (POTS, CRPS, and CFS), but which do not report explicit diagnoses. While the causal association between HPV vaccination and these AEs remains uncertain, more extensive analyses of spontaneous reports can better identify the relevant case series for thorough signal evaluation.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research