[Prevalence and clinical significance of interactions drug-enteral nutrition in Intensive Care Units].

[Prevalence and clinical significance of interactions drug-enteral nutrition in Intensive Care Units]. Rev Bras Enferm. 2014 Jan;67(1):85-90 Authors: Reis AM, Carvalho RE, Faria LM, Oliveira RC, Zago KS, Cavelagna MF, Silva AG, Neto ML, Cassiani SH Abstract This is a multicenter, cross-sectional retrospective study, which aimed to determine the prevalence of interactions drug-enteral nutrition (EN) in Intensive Care Units (ICU) of seven teaching hospitals in Brazil, and to analyze the clinical significance of them. Information on medications and EN administered with 24 hours and 120 hours of hospitalization were collected. For identification of drug-EN interaction was employed software Drug Reax®. It was investigated 1.124 records. Of these, 320 patients, with 24 hours of hospitalization, were on EN, and 20 (6.3%) had drug-EN interaction. Of the 504 patients with 120 hours of hospitalization, 39 (7.7%) had drug-EN interaction. The most frequent drug-EN interactions of clinical significance were phenytoin-EN, warfarin-EN and levothyroxine-EN. Drug-EN interactions may interfere with the quality and cost effectiveness of care in ICU, so it is essential that the health team has knowledge about them. PMID: 24676073 [PubMed - in process]
Source: Revista Brasileira de Enfermagem - Category: Nursing Authors: Tags: Rev Bras Enferm Source Type: research