Class 2 Medicines Recall: Wockhardt UK Ltd, Levothyroxine 100micrograms/5ml Oral Solution
Wockhardt UK Ltd is recalling specific batches of... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - January 30, 2020 Category: Drugs & Pharmacology Source Type: news

Levothyroxine-induced Liver Injury Levothyroxine-induced Liver Injury
Drug-induced liver injury is rarely observed with levothyroxine therapy; this case demonstrates that it can be reversible with cessation of the drug.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 21, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Jury Still Out on Whether to Treat Subclincal Hypothyroidism in Elderly Jury Still Out on Whether to Treat Subclincal Hypothyroidism in Elderly
A new systematic review suggests elderly patients with overt hypothyroidism should receive levothyroxine treatment, but for those with subclinical hypothyroidism, the advice is less certain.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - December 13, 2019 Category: Cardiology Tags: Diabetes & Endocrinology News Source Type: news

Jury Still Out on Whether to Treat Subclinical Hypothyroidism in Elderly Jury Still Out on Whether to Treat Subclinical Hypothyroidism in Elderly
A new systematic review suggests elderly patients with overt hypothyroidism should receive levothyroxine treatment, but for those with subclinical hypothyroidism, the advice is less certain.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - December 13, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

' Growing Concern': Incorrect Doses of Compounded Levothyroxine'Growing Concern': Incorrect Doses of Compounded Levothyroxine
"Dramatic" variations in the amount of active ingredient were found in compounded liquid versions of levothyroxine (LT4) in a new study. The"surprise" results are a cause for concern, say researchers.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 13, 2019 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Mifepristone Increases TH Requirements in Hypothyroidism Mifepristone Increases TH Requirements in Hypothyroidism
Treatment with mifepristone resulted in increased levothyroxine requirements among patients with Cushing disease and central hypothyroidism.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Outcome in Heart Failure Treated With Levothyroxine Outcome in Heart Failure Treated With Levothyroxine
A new study examines the long-term effects of levothyroxine treatment in patients with heart failure. What have we learned?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Lannett Enters Into Distribution Agreement For Levothyroxine
PHILADELPHIA, July 8, 2019 -- (Healthcare Sales & Marketing Network) -- Lannett Company, Inc. (NYSE: LCI) today announced that it has entered into a future exclusive supply and distribution agreement for the approved Levothyroxine Sodium Tablets USP of Ce... Biopharmaceuticals, Generics, Distribution Lannett Company, Levothyroxine, Cediprof, Neolpharma Pharmaceutical Group (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 8, 2019 Category: Pharmaceuticals Source Type: news

Generic vs Brand-Name Levothyroxine: Same Cardiac Event Risk? Generic vs Brand-Name Levothyroxine: Same Cardiac Event Risk?
' There's been a lot of discussion of generic versus brand L-T4, and this is just one other piece of information in a very large group of patients, but it needs follow-up studies,'says lead author.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - July 2, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Similar CV Event Rates Seen for Generic, Brand Levothyroxine
THURSDAY, June 27, 2019 -- Cardiovascular event rates are similar for patients with newly treated hypothyroidism receiving generic and brand levothyroxine (L-T4), according to a study published online April 26 in the Mayo Clinic Proceedings. Robert... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2019 Category: Pharmaceuticals Source Type: news

Over-prescribed levothyroxine: Mayo Clinic Radio Health Minute
The most commonly prescribed drug in the U.S. also may be one of the most overprescribed for older individuals. Levothyroxine is a medication used to treat low thyroid hormone levels. However, a study published this spring in the New England Journal of Medicine reported that patients with subclinical thyroid hormone levels received no benefit from the drug. Mayo [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 21, 2019 Category: Databases & Libraries Source Type: news

Study finds similar cardiovascular outcomes for generic, brand-name drugs for hypothyroidism
JACKSONVILLE, Fla. -- A new study by Mayo Clinic researchers may have broad implications for treatment of patients with predominantly benign thyroid disease and newly treated hypothyroidism. The study, to be published in Mayo Clinic Proceedings in July, looked at whether generic and brand-name levothyroxine therapy affected hospitalization for cardiovascular events for those patients who [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 19, 2019 Category: Databases & Libraries Source Type: news

Westminster Pharmaceuticals, LLC. Issues Voluntary Nationwide Recall of Levothyroxine and Liothyronine (Thyroid Tablets, USP) Due to Risk of Adulteration
Westminster Pharmaceuticals, LLC is voluntarily recalling all lots, within expiry, of Levothyroxine and Liothyronine (Thyroid Tablets, USP) 15 mg, 30 mg, 60 mg, 90 mg,& 120 mg to the wholesale level. These products are being recalled as a precaution because they were manufactured using active pharmaceutical ingredients that were sourced prior to the FDA ’s Import Alert of Sichuan Friendly Pharmaceutical Co., Ltd., which as a result of a 2017 inspection were found to have deficiencies with Current Good Manufacturing Practices (cGMP). Substandard cGMP practices could represent the possibility of risk being introduc...
Source: FDA Center for Drug Evaluation and Research - What's New - May 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Why doctors now warn against routinely treating mild thyroid issues
Giving daily levothyroxine pills to people with a mild abnormality called subclinical hypothyroidism offers no benefit, a review of 21 clinical trials suggests. (Source: CBC | Health)
Source: CBC | Health - May 17, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Mild Hypothyroidism Being Overtreated, Avoid Pills, Says Panel Mild Hypothyroidism Being Overtreated, Avoid Pills, Says Panel
In a"strong recommendation," an international panel of experts advise that patients with subclinical hypothyroidism should not be routinely prescribed levothyroxine; evidence shows few benefits.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - May 16, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Hundreds of thousands of people in the UK may be unnecessarily taking drugs
Figures from NHS Digital show that more than 32million prescriptions were issued in England in 2018 for levothyroxine. This is up from 20,426,378 in 2008. (Source: the Mail online | Health)
Source: the Mail online | Health - May 15, 2019 Category: Consumer Health News Source Type: news

TSH and Pregnancy: Finding Your Way Out of the Gray Zone TSH and Pregnancy: Finding Your Way Out of the Gray Zone
Which patients with subclinical hypothyroidism in pregnancy would benefit from levothyroxine treatment? Dr Korevaar shares three tips to help guide the decision-making process.Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 9, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

ENDO: Levothyroxine Does Not Up Fertility in Women With TPO Ab
TUESDAY, March 26, 2019 -- For euthyroid women with thyroid peroxidase antibodies and a history of miscarriage or infertility, levothyroxine does not result in an increased rate of live births versus placebo, according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 26, 2019 Category: Pharmaceuticals Source Type: news

Levothyroxine provides no pregnancy benefits to women with thyroid antibodies
According to data, presented at the Endocrine Society's annual meeting, euthyroid women treated with levothyroxine did not have improved chances of having a live birth, if they were also positive for thyroid antibodies.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 26, 2019 Category: Endocrinology Source Type: news

Levothyroxine Tx Doesn't Deliver in Women With TPO Antibodies
(MedPage Today) -- Preterm births and neonatal outcomes not significantly different than placebo (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 23, 2019 Category: OBGYN Source Type: news

Levothyroxine treatment in women with thyroid antibodies may not increase live birth rate
(University of Birmingham) Treating women with thyroid antibodies but a normal thyroid function with a medicine called Levothyroxine does not make them more likely to deliver a live baby, new research suggests. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2019 Category: International Medicine & Public Health Source Type: news

Levothyroxine treatment in women with thyroid antibodies may not increase live birth rate
(The Endocrine Society) Treating women who have thyroid antibodies, but normal thyroid function, with a medicine called Levothyroxine does not make them more likely to deliver a live baby, new research from the United Kingdom suggests. The research will be presented Saturday, March 23 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La., and published in the New England Journal of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2019 Category: International Medicine & Public Health Source Type: news

Levothyroxine Dosing: Morning, Night, or In Between? Levothyroxine Dosing: Morning, Night, or In Between?
Clinicians have traditionally told patients to take levothyroxine first thing in the morning, at least an hour before any food or drink. But does it really matter? Dr Leung looks at the evidence.Medscape Diabetes & Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - March 22, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology Article Source Type: news

Merck Wins Lawsuit on Levothyroxine Saga in France Merck Wins Lawsuit on Levothyroxine Saga in France
Merck has prevailed in a first lawsuit that claimed that switching the formulation of levothyroxine in France caused patients harm. The company still faces further claims, however.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 13, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

PCOS Gene Variants; Testosterone and CAD; New Generic Levothyroxine
(MedPage Today) -- News and commentary from the endocrinology world (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - December 28, 2018 Category: OBGYN Source Type: news

TH Status During Levothyroxine Therapy in Hypothyroidism TH Status During Levothyroxine Therapy in Hypothyroidism
Does levothyroxine therapy effectively restore thyroid hormone signaling in patients with overt hypothyroidism?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Euthyrox (Levothyroxine Sodium Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

Lannett signs $50M distribution deal; stock up 10 percent
Lannett Co. Inc. entered into an agreement Monday with Amneal Pharmaceuticals Inc., under which Amneal will be the sole customer for Lannett's levothyroxine sodium tablets. The deal calls for Lannett, a Northeast Philadelphia generic drug company, to receive an upfront payment of $50 million. Other terms of the transaction were not disclosed. Lannett's stock opened up 10 percent at $5.88 per share Monday morning. The deal comes about three months after Lannett (N YSE: LCI) announced Jerome Stevens… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 12, 2018 Category: Pharmaceuticals Authors: John George Source Type: news

Lannett Enters Into Agreement With Amneal Pharmaceuticals For Levothyroxine
Lannett Locks in $50 Million of Gross Profit for 16-Week Period PHILADELPHIA, Nov. 12, 2018 -- (Healthcare Sales & Marketing Network) -- Lannett Company, Inc. (NYSE: LCI) today announced that it has entered into an agreement with Amneal Pharmaceuticals... Biopharmaceuticals, Generics, Distribution Lannett Company, Amneal Pharmaceuticals, Levothyroxine (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 12, 2018 Category: Pharmaceuticals Source Type: news

levothyroxine sodium (Synthroid, Levoxyl)
Title: levothyroxine sodium (Synthroid, Levoxyl)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/5/2018 12:00:00 AM (Source: MedicineNet Thyroid General)
Source: MedicineNet Thyroid General - November 5, 2018 Category: Endocrinology Source Type: news

The Love-Hate Relationship With Levothyroxine The Love-Hate Relationship With Levothyroxine
Levothyroxine, despite being the most prescribed drug in the United States, has many patients disenchanted and looking to T3 for symptom relief. How should clinicians approach the T4/T3 controversy?Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 25, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Article Source Type: news

Hypothyroidism drug improved with zinc
The new drug poly-zinc-liothyronine may perform better than liothyronine in patients with hypothyroidism who do not respond to levothyroxine, according to research published inThyroid.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 15, 2018 Category: Endocrinology Source Type: news

Cholesterol Levels Remain High Despite T4 for Hypothyroidism Cholesterol Levels Remain High Despite T4 for Hypothyroidism
Despite their TSH levels being normalized with levothyroxine treatment, patients with hypothyroidism continue to show elevated cholesterol, a sign of continued thyroid signaling dysfunction.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 3, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Why Lannett's stock opened down 55 percent
Lannett Co. Inc. ’s stock opened down 55 percent, at $5.95 a share, Monday after the Northeast Philadelphia generic pharmaceutical maker announced a key distribution agreement was not being renewed. The distribution agreement with Jerome Stevens Pharmaceuticals (JSP), which will expire March 23, 2019, covers thre e JSP products: butalbital, aspirin, caffeine with codeine phosphate capsules; digoxin tablets; and levothyroxine sodium tablets. Tim Crew, Lannett’s CEO said the Steinlauf family, which… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - August 20, 2018 Category: American Health Authors: John George Source Type: news

Recall Alert: FDA Warning About Two Thyroid Medications
By Sandee LaMotte, CNN (CNN) — Certain batches of hypothyroid medications are being recalled by Westminster Pharmaceuticals after one of its Chinese suppliers failed a US Food and Drug Administration inspection. The medication in question contains a combination of levothyroxine, called LT4, and liothyronine, called LT3. Both are synthetic thyroid hormones used when a person’s thyroid gland is no longer functioning properly. “While we stand behind the quality of our product, we are taking the utmost precaution by recalling our Thyroid, USP Tablets only to the wholesale level due to a recent inspection by t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 15, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Thyroid Source Type: news

Thyroid Tablets Recalled in US Because of Impurity Risk Thyroid Tablets Recalled in US Because of Impurity Risk
The combined levothyroxine (T4) and liothyronine (T3) thyroid tablets from Westminster Pharmaceuticals are being recalled to the wholesale level as a precaution because of a risk of adulteration.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 13, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Alert Source Type: news

Westminster Pharmaceuticals, LLC. Issues Voluntary Nationwide Recall of Levothyroxine and Liothyronine (Thyroid Tablets, USP) Due to Risk of Adulteration
Westminster Pharmaceuticals, LLC is voluntarily recalling all lots, within expiry, of Levothyroxine and Liothyronine (Thyroid Tablets, USP) 15 mg, 30 mg, 60 mg, 90 mg,& 120 mg to the wholesale level. These products are being recalled as a precaution because they were manufactured using active pharmaceutical ingredients that were sourced prior to the FDA ’s Import Alert of Sichuan Friendly Pharmaceutical Co., Ltd., which as a result of a 2017 inspection were found to have deficiencies with Current Good Manufacturing Practices (cGMP). Substandard cGMP practices could represent the possibility of risk being introduc...
Source: Food and Drug Administration - August 10, 2018 Category: Food Science Source Type: news

Tinkering With Levothyroxine: Does It Make a Difference? Tinkering With Levothyroxine: Does It Make a Difference?
Most physicians will carefully titrate levothyroxine to help their patients with hypothyroidism reach the TSH value at which they feel their best. But does it actually make a difference?Medscape Diabetes & Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 6, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Commentary Source Type: news

Low levothyroxine doses during childhood linked to transient congenital hypothyroidism
A study inThyroid suggests that children given a lower dose of levothyroxine were more likely to develop transient congenital hypothyroidism, compared to those on a higher dose.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - July 12, 2018 Category: Endocrinology Source Type: news

Prehospital Assessment for Stroke Isn ’t Perfect
Prehospital assessment tools for neurological deficits aren’t perfect An approximately 30-year-old male answers the door to let you and your partner into the house you’ve been called to. Hank introduces himself and thanks you for coming, quickly adding that he’s concerned about his mother who’s “acting weird.” Hank tells you he stopped by his mom’s house for lunch and found her using paper plates to heat food on the stove. He stopped her before the plate ignited. His mother seemed confused and so he called 9-1-1. Patient Assessment Margaret, Hank’s 53-year-old mot...
Source: JEMS Patient Care - May 1, 2018 Category: Emergency Medicine Authors: Dennis Edgerly, EMT-P Tags: Patient Care Cardiac & Resuscitation Columns Source Type: news

Increased risk of mortality in older patients on levothyroxine
In some elderly patients with subclinical hypothyroidism, treatment with levothyroxine is linked to a higher risk of mortality, research presented at ENDO 2018 reports.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 21, 2018 Category: Endocrinology Source Type: news

Levothyroxine use linked to increased bone fracture
A study in theJournal of Bone and Mineral Research suggests that levothyroxine dose may be linked to the incidence of fractures in thyroid cancer patients. Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 20, 2018 Category: Endocrinology Source Type: news

Levothyroxine may improve fertility in Hashimoto ’s patients
For women with infertility and Hashimoto’s thyroiditis, levothyroxine treatment can improve ovarian function, according to a study published inThe Journal of Obstetrics and Gynaecology Research.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 12, 2018 Category: Endocrinology Source Type: news

Levothyroxine Dose Adjustment in Hypothyroid Pregnant Women Levothyroxine Dose Adjustment in Hypothyroid Pregnant Women
This study assesses two algorithms for levothyroxine dose adjustment in hypothyroid women during pregnancy. How do they compare?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 19, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Levothyroxine No Help for Pregnant Women with Thyroid Autoantibodies (CME/CE)
(MedPage Today) -- Hormone did not improve outcomes in women undergoing fertility treatment (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - December 12, 2017 Category: Endocrinology Source Type: news

Second Trimester Levothyroxine and Outcomes in Children Second Trimester Levothyroxine and Outcomes in Children
Is levothyroxine therapy during pregnancy associated with significantly improved IQs in offspring?Evidence-Based Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 2, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

An Avoidable Mistake and a Wake-Up Call
Jane Doe was a frail 81-year-old female resident who had resided in a skilled nursing facility for 18 months. Her medical history included hypothyroidism from having had a total thyroidectomy when she was a young adult. She required levothyroxine daily. (Source: Caring for the Ages)
Source: Caring for the Ages - October 28, 2017 Category: Health Management Authors: William C. Wilson Tags: LEGAL ISSUES Source Type: news

Levothyroxine Dose Tweaks Don't Alter Symptoms in Hypothyroidism Levothyroxine Dose Tweaks Don't Alter Symptoms in Hypothyroidism
Patients randomized to target either low-normal or high-normal thyroid levels with levothyroxine treatment show no significant differences in cognitive, mood, or quality-of-life measures.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 25, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Side Effects Skyrocket in France With Levothyroxine Reformulation Side Effects Skyrocket in France With Levothyroxine Reformulation
Merck is being pressured to make the previous formulation available, despite concerns and limited supplies.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 11, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news