The Effects of Hematopoietic Stem Cell Transplant on Splenic Extramedullary Hematopoiesis in Patients with Myeloproliferative Neoplasm-associated Myelofibrosis

Conclusion HSCT reduces/abrogates splenic EMH and is associated with an increased number of Gamna–Gandy bodies, which may suggest vascular damage. The lack of stromal changes in spleens removed shortly after transplant is in line with similar observations in the BM, where a longer interval is often necessary for resolution of fibrosis.
Source: Hematology Oncology and Stem Cell Therapy - Category: Cancer & Oncology Source Type: research