Efficacy of vaginally applied estrogen, testosterone, or polyacrylic acid on vaginal atrophy: a randomized controlled trial

Conclusions: After a 12-week treatment with testosterone and estrogen compared with placebo lubrication, there was a significant improvement in vaginal trophism in postmenopausal women with vaginal atrophy.
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research

Related Links:

AbstractPurposeTo report the clinical, ultrasound and histopathological characteristics, clinical management, and prognosis of 13 patients with Sertoli-Leydig cell tumors (SLCTs) of ovary.Methods13 patients with pathologically confirmed ovarian SLCTs at International Peace Maternity and Child Health Hospital from 2010 and 2019 were included in this study. The clinical, ultrasound and histopathological characteristics, clinical management, and prognosis of 13 patients were retrospectively analyzed.ResultsThe age ranged 25 –68 years. Of the 8 (62%) patients presenting endocrine symptoms, 4 had post-menopausal hemo...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Authors: Luna Russo MA, Chalif JN, Falcone T Abstract Endometriosis is a disease of reproductive age women that is commonly characterized by symptoms that often negatively impact quality of life. The clinical management of endometriosis remains highly variable and mostly influenced by geographic location, practice patterns, and breadth of clinician experience. This variability in treatment has inspired a trend towards multidisciplinary and specialized care of patients suffering from this disease. Surgical sampling, followed by histologic confirmation of endometrial-like tissue, remains the standard for the definiti...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Authors: Terzic M, Aimagambetova G, Norton M, Della Corte L, Marín-Buck A, Lisón JF, Amer-Cuenca JJ, Zito G, Garzon S, Caruso S, Rapisarda AMC, Cianci A Abstract Adnexal masses are a common finding in women, with 20% of them developing at least one pelvic mass during their lifetime. There are more than 30 different subtypes of adnexal tumours, with multiple different subcategories, and the correct characterisation of the pelvic masses is of paramount importance to guide the correct management. On that basis, different algorithms and scoring systems have been developed to guide the clinical assessment....
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
This study sought to evaluate the prevalence of menopausal symptoms in a population of reproductive-aged women remote from cancer therapy compared with a group of healthy similar-aged controls and with a cohort of late reproductive-aged (LR) controls.MethodsParticipants were assessed for symptoms of menopause, early follicular phase hormones, and ultrasound examinations. Menopausal symptoms were analyzed in exposed participants and controls usingχ2 analyses, Wilcoxon-Mann Whitney tests, and multivariable logistic regression models.ResultsOne hundred seventy cancer survivors, 135 similar-aged controls, and 71 LR control...
Source: Journal of Cancer Survivorship - Category: Cancer & Oncology Source Type: research
SummaryTo determine whether ultrasound features can improve the diagnostic performance of tumor markers in distinguishing ovarian tumors, we enrolled 719 patients diagnosed as having ovarian tumors at Nanfang Hospital from September 2014 to November 2016. Age, menopausal status, histopathology, the International Federation of Gynecology and Obstetrics (FIGO) stages, tumor biomarker levels, and detailed ultrasound reports of patients were collected. The area under the curve (AUC), sensitivity, and specificity of the bellow-mentioned predictors were analyzed using the receiver operating characteristic curve. Of the 719 patie...
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - Category: Research Source Type: research
CONCLUSION: In these DICER1-carrier females, DICER1-related gynecological tumors occurred during childhood or adolescence in some after which women generally experienced healthy reproductive lives. Individual education and screening for these tumors is warranted. The high rate of DICER1-related multinodular goiter resulting in pre- and post-pregnancy thyroidectomy underscores the importance of thyroid monitoring during pregnancy to ensure maternal and fetal wellbeing. PMID: 31952842 [PubMed - as supplied by publisher]
Source: Gynecologic Oncology - Category: Cancer & Oncology Authors: Tags: Gynecol Oncol Source Type: research
AbstractBackgroundObstetric anal sphincter injury is the most frequent cause of fecal incontinence (FI) in young women. However, the relationship between the extent of anal sphincter defects and the severity of long-term FI (at least 1 year after delivery) has been poorly studied. The aim of the present study was to determine if, in the long term, the extent of anal sphincter defects graded at anal endosonography was linked with the severity of FI.MethodsA retrospective study was conducted on women with a history of vaginal delivery, who presented with FI and had three-dimensional anorectal high-resolution manometry and en...
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
A 58-year-old woman with enlarging fibroid uterus in menopause presented for gynecologic evaluation. The enlarging, pedunculated, exophytic fibroid measuring 8.7  × 10 × 10 cm was noted incidentally on CT performed for an episode of acute abdominal pain attributed to diverticulitis. Three years earlier, the fibroid measured 4.0 × 4.2 × 3.9 cm on transvaginal ultrasound. Given the concern for an enlarging fibroid in menopause, MRI was perf ormed which showed a pedunculated fundal fibroid measuring 8.5 × 7.2 × 9.2 cm and progressively enhancing right ovarian cyst me...
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Images in Gynecological Surgery Source Type: research
A 58-year-old woman with an enlarging uterine myoma in menopause presented for gynecologic evaluation. The enlarging, pedunculated, exophytic myoma measuring 8.7  × 10 × 10 cm was noted incidentally on computed tomography performed for an episode of acute abdominal pain attributed to diverticulitis. Three years earlier, the myoma measured 4.0 × 4.2 × 3.9 cm on the transvaginal ultrasound. Given the concern for an enlarging myoma in menopa use, magnetic resonance imaging was performed, which showed a pedunculated fundal myoma measuring 8.5 × 7.2 × 9.2 cm and a prog...
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Images in Gynecologic Surgery Source Type: research
Ovarian reserve represents the number of available follicles/oocytes within ovaries and this can be assessed by measuring follicle stimulating hormone (FSH) levels, anti-M üllerian hormone (AMH) levels, and/or antral follicle count (AFC) determined by ultrasound [1]. AMH is produced in women by the granulosa cells of developing follicles and represents a marker of ovarian reserve that can be used in assisted reproduction and for prediction of menopausal age, probabil ity of natural conception, assessment of ovarian function after gonadotoxic treatment or diagnosis of polycystic ovarian syndrome [2], although its relia...
Source: Maturitas - Category: Primary Care Authors: Source Type: research
More News: Clinical Trials | Estradiol | Health | Laboratory Medicine | Men | Menopause | OBGYN | Study | Ultrasound | Women