Association of Down syndrome and tuberous sclerosis and their similarities in m-TOR pathway overactivation. About a case

Conclusions Neurological and cardiac implications in patients with DS/TSC association lead to a difficult therapeutic scenario with a high rate of complications, partially due to symptomatic refractoriness. New drugs aimed at the m-TOR signalling pathway could be very useful in this picture, given its relationship to improvement of cognitive impairment and tumours associated with these two entities.
Source: International Medical Review on Down Syndrome - Category: Disability Source Type: research