Renal replacement therapy neutralizes elevated MIF levels in septic shock

Conclusions This is the first study investigating the effect of efficient MIF removal from the plasma pool of patients with septic shock. Reduction of high circulating MIF by CRRT therapy was accompanied by improved survival. Thus, targeted removal of MIF from the circulating blood pool might be a promising approach to reduce mortality in severe sepsis.
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research