Mimicking the cardiac cycle in intact cardiomyocytes using diastolic and systolic force clamps; measuring power output
Conclusion
Here, we introduce a new approach that by combining mechanics, electronics, and a new type optical force transducer can measure the FL relationship of a single isolated cardiomyocyte undergoing a mechanical loop that mimics the PV cycle of a beating heart.
Source: Cardiovascular Research - Category: Cardiology Authors: Helmes, M., Najafi, A., Palmer, B. M., Breel, E., Rijnveld, N., Iannuzzi, D., van der Velden, J. Tags: Cardiac biology and remodelling Source Type: research