Association of interleukins genes polymorphisms with multi-drug resistant tuberculosis in Ukrainian population.

CONCLUSIONS: Heterozygous genotype and mutations homozygous genotypes gene in polymorphisms determining specified cytokines' production is a PT risk factor and may lead to disease progression into chronic phase. Heterozygous genotype of aforementioned cytokine genetic polymorphisms was significantly the most frequent in patients with MDR TB. PMID: 27238179 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/27238179?dopt=Abstract

Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Butov DO, Kuzhko MM, Makeeva NI, Butova TS, Stepanenko HL, Dudnyk AB Tags: Pneumonol Alergol Pol Source Type: research