Stem cells: RAAS inhibition promotes podocyte replacement

Nature Reviews Nephrology 12, 316 (2016). doi:10.1038/nrneph.2016.66 Author: Jessica K. Edwards A new study finds that inhibition of the renin–angiotensin–aldosterone system (RAAS) during focal segmental glomerulosclerosis (FSGS) augments the ability of cells of renin lineage (CoRL) to proliferate and differentiate into podocytes. Stuart Shankland et al. permanently labelled CoRL in mice and then experimentally
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research