Endogenous interleukin-17 as a factor determining severity of Clostridium difficile infection in mice.

In conclusion, the present data demonstrate that endogenous IL-17 may be a factor determining severity of CDI in mice. Although the mechanism was fully unknown, IL-17-mediated inflammatory responses, such as cytokine/chemokine productions and neutrophil accumulation, may be plausible targets for future investigations. Key words: Clostridium difficile, Interleukin-17, neutrophils, mice model.
PMID: 27166143 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - May 9, 2016 Category: Microbiology Authors: Nakagawa T, Mori N, Kajiwara C, Kimura S, Akasaka Y, Ishii Y, Saji T, Tateda K Tags: J Med Microbiol Source Type: research