Recent Advances in Renal Hypoxia: Insights from Bench Experiments and Computer Simulations.

Recent Advances in Renal Hypoxia: Insights from Bench Experiments and Computer Simulations. Am J Physiol Renal Physiol. 2016 May 4;:ajprenal.00228.2016 Authors: Layton AT Abstract The availability of oxygen in renal tissue is determined by the complex interactions among a host of processes, including renal blood flow, glomerular filtration, arterial-to-venous oxygen shunting, medullary architecture, Na$^+$ transport, and oxygen consumption. When this delicate balance is disrupted, the kidney may become susceptible to hypoxic injury. Indeed, renal hypoxia has been implicated as one of the major causes of acute kidney injury and chronic kidney diseases. This review highlights recent advances in our understanding of renal hypoxia; some of these studies were published in response to a recent Call for Papers of this journal: Renal Hypoxia. PMID: 27147670 [PubMed - as supplied by publisher]
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Tags: Am J Physiol Renal Physiol Source Type: research