Evaluation of myocardial strain and artery elasticity using speckle tracking echocardiography and high-resolution ultrasound in patients with bicuspid aortic valve

Abstract Reduced artery elasticity and reduced myocardial strain were present in patients with bicuspid aortic valve (BAV). Their relation to dilation of proximal aorta is unclear. We aimed to study their relation to dilation of proximal aorta. We studied 57 BAV patients categorized into 2 subgroup according to proximal ascending aortic dimensions (nondilated <35 mm and dilated ≥35 mm). Twenty-nine healthy subjects were recruited as control. Aortic and carotid strain, distensibility and stiffness index were derived. Left ventricular myocardial strain were acquired with speckle-tracking echocardiography. BAV patients with dilation of proximal ascending aorta had lower aortic strain (4.1 ± 4.2 % vs. 7.1 ± 3.5 %) and carotid strain (4.8 ± 1.9 % vs. 10.6 ± 4.2 %), lower aortic distensibility (1.4 ± 1.5 cm2 dyn−1 10−6 vs. 2.5 ± 1.5 cm2 dyn−1 10−6) and carotid distensibility (1.6 ± 0.7 cm2 dyn−1 10−6 vs. 3.9 ± 2.4 cm2 dyn−1 10−6), higher aortic stiffness index (19.7 ± 14.1 vs. 8.3 ± 4.9) and carotid stiffness index (12.2 ± 8.5 vs. 5.0 ± 2.2), and lower global circumferential (−15.9 ± 5.8 % vs. −19.1 ± 4.1 %), radial (19.3 ± 11.6 % vs. 29.8 ± 14.9 %) and longitudinal (−15.7 ± 3.4 % vs. −18.4 ± 3.4 %) compared with those without dilation of proximal ascending aorta. All mean values are different to p < 0.05. ...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research