Extension Study to Assess the Safety and Efficacy of Repeated AbobotulinumtoxinA Injections in Adults with Upper Limb Spasticity (P3.307)

Conclusions: Safety analysis in this long term study did not generate any new unexpected safety findings; safety profile was similar across doses. Repeated abobotulinumtoxinA injections were associated with sustained or progressive improvement in muscle tone, perceived function (DAS) and global assessment in ULS patients post stroke/TBI. Supported by:IpsenDisclosure: Dr. Brashear has received personal compensation for activities with Allergan, Ipsen, Revance and Concerta as a consultant. Dr. Brashear has received royalty payments from books royalties. Dr. Brashear has received research support from Ipsen, Merz, Allerg Dr. Marciniak has nothing to disclose. Dr. Edgley has received research support from Ipsen. Dr. Gul has received research support from FG as an investigator in an Ipsen trial. Dr. Hedera has nothing to disclose. Dr. McAllister has received personal compensation for activities with Teva CNS, Allergan, Mallinckrodt, Ipsen, Merz Pharmaceuticals, Depomed, Pfizer and XenoPort as a speaker. Dr. O'Dell has received research support from Ipsen. Dr. Rubin has received personal compensation for activities with Allergan and Merz as a speaker. Dr. Walker has received research support from Ipsen. Dr. Vilain has received personal compensation for activities with Ipsen Innovation as an employee. Dr. Mahmood has received personal compensation for activities with Ipsen as an employee. Dr. Gracies has received research support from Ipsen.

Source: Neurology - April 3, 2016 Category: Neurology Authors: Brashear, A., Marciniak, C., Edgley, S., Gul, F., Hedera, P., McAllister, P., O'Dell, M., Rubin, B., Walker, H., Vilain, C., Mahmood, A., Gracies, J.-M. Tags: Neurorehabilitation Source Type: research