Validation of the 17‐item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN‐AMPS) data

ConclusionsOur results support the consensus definition of response based on HDRS‐17 scores (>50% decrease from baseline). A similar definition of response may apply to the HDRS‐7 and Bech‐6. Copyright © 2016 John Wiley & Sons, Ltd.

Source: Human Psychopharmacology: Clinical and Experimental - March 1, 2016 Category: Psychiatry Authors: William V. Bobo, Gabriela C. Angleró, Gregory Jenkins, Daniel K. Hall‐Flavin, Richard Weinshilboum, Joanna M. Biernacka Tags: Research Article Source Type: research