Abstract A42: Inhibition of the invasive component of mucinous breast cancers by targeting c-kit

Conclusions: Targeting c-kit may represent a new type of therapy for some mucinous breast cancers. This is the first study to examine estrogen regulated genes in a model of mucinous breast cancer, allowing identification of genetic pathways that cause more indolent pure mucinous tumors to switch to aggressive mixed mucinous tumors.Citation Format: J. Chuck Harrell, Megan J. Blatner, Britta M. Jacobsen. Inhibition of the invasive component of mucinous breast cancers by targeting c-kit. [abstract]. In: Proceedings of the AACR Special Conference on Advances in Breast Cancer Research; Oct 17-20, 2015; Bellevue, WA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(2_Suppl):Abstract nr A42.

Source: Molecular Cancer Research - February 29, 2016 Category: Cancer & Oncology Authors: Harrell, J. C., Blatner, M. J., Jacobsen, B. M. Tags: Luminal Breast Cancer: Poster Presentations - Proffered Abstracts Source Type: research