An Important Finding of Systemic Aspergillosis: Skin Involvement and Amphotericin B Resistance in an Adolescent

Invasive aspergillosis is a life-threatening infectious complication in immunocompromised patients, especially with malignancy, and in some cases, it causes extensive tissue destruction and subsequent systemic illness, leading to multiorgan failure and death. Skin involvement and amphotericin B resistance are very rare findings of aspergillosis. Herein, we report the case of a primary hemophagocytic syndrome patient who developed subcutaneous nodules in the 3rd month of bone marrow transplantation from which Aspergillus fumigatus was cultivated despite the fact that she was under antifungal therapy.

Source: Pediatrics and Neonatology - December 9, 2013 Category: Perinatology & Neonatology Authors: Aslinur Ozkaya-Parlakay, Buse Ozer-Bekmez, Ates Kara, Baris Kuskonmaz, Zuhal Akcoren, Sevtap Arikan-Dagli, Berna Oguz Tags: Case report Source Type: research