Role of serum biomarkers in the prediction of outcome in women with threatened miscarriage: a systematic review and diagnostic accuracy meta-analysis

CONCLUSIONS
In women with threatened miscarriage, serum CA 125 has high predictive value in identifying pregnancies that are ‘likely to continue’, whereas the most commonly used biomarkers of serum hCG and progesterone are not useful in predicting outcome of a pregnancy with a viable fetus. Other markers such as inhibin A and a combination of markers need to be investigated to hopefully improve the prediction of outcome in women with threatened miscarriage.

Source: Human Reproduction Update - February 16, 2016 Category: OBGYN Authors: Pillai, R. N., Konje, J. C., Tincello, D. G., Potdar, N. Tags: Reviews Source Type: research