Adult Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia in Daily Practice: A Multicenter Experience

Conclusions Current state-of-the art management of Ph+ ALL in real-life seems to be incorporation of TKIs to chemotherapy regimens and proceeding to allo-HCT, whenever possible. Teaser In this retrospective, multicenter study, we evaluated the real-life outcomes of adult Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL) patients. The best results in terms of survival are achieved in patients, who were treated with tyrosine kinase inhibitors during induction and received allogeneic hematopoietic cell transplantation as part of consolidation.
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research