New way to detect human-animal diseases tested in lemurs

(Duke University) RNA sequencing is uncovering emerging diseases in wildlife that other diagnostic tests cannot detect. Researchers used a technique called transcriptome sequencing to screen for blood-borne diseases in Madagascar's lemurs, distant primate cousins to humans. The animals were found to be carrying several previously unknown parasites similar to those that cause Lyme disease in humans. The approach could pave the way for earlier, more accurate detection of disease outbreaks that move between animals and people.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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Abstract: Lyme disease is the most commonly reported vector-borne disease in the United States. After initial antibiotic treatment for patients with Lyme disease, ongoing symptoms that may persist have considerable long-term impact on healthcare costs. Posttreatment Lyme disease syndrome is characterized by a host of chronic symptoms that can leave patients physically and mentally disabled.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature: LYME DISEASE Source Type: research
Publication date: Available online 20 July 2018Source: Ticks and Tick-borne DiseasesAuthor(s): Tammi L. Johnson, Christine B. Graham, Sarah E. Maes, Andrias Hojgaard, Amy Fleshman, Karen A. Boegler, Mark J. Delory, Kimetha S. Slater, Sandor E. Karpathy, Jenna K. Bjork, David F. Neitzel, Elizabeth K. Schiffman, Rebecca J. EisenAbstractIn the north-central United States, the blacklegged tick (Ixodes scapularis) is currently known to vector seven human pathogens. These include five bacteria (Borrelia burgdorferi sensu stricto, Borrelia mayonii, Borrelia miyamotoi, Anaplasma phagocytophilum, Ehrlichia muris eauclairensis), one...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 20 July 2018Source: TrAC Trends in Analytical ChemistryAuthor(s): Yunlei Xianyu, Qiaoling Wang, Yiping ChenAbstractPoint-of-care testing (POCT) for early diagnosis and personalized treatment in clinics plays an increasingly important role in controlling the outbreak of disease and improving the survival rate of patients. Magnetic particles (MPs) have emerged as promising candidates for developing biosensors for POCT. This review outlines the mechanisms of assaying biomarkers by MPs, and discusses recent advances in MPs-implemented biosensors with enhanced performance and reduced complexit...
Source: TrAC Trends in Analytical Chemistry - Category: Chemistry Source Type: research
ConclusionsThe experimental results from the pharmacological research enable the validation of their traditional uses in several of the groups of diseases in the countries of origin and reveal these plants to be a valuable source for therapeutic molecules. However, more toxicity assays and clinical trials would be necessary to establish optimal and safe doses of consumption on the application of these medicinal plants.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 24 March 2018Source: Advances in Space ResearchAuthor(s): Salvatore Sarno, Maria Daniela Graziano, Giancarmine Fasano, Marco D'ErricoAbstractThis paper presents an original approach for a radar-based distributed system. The novel mission concept foresees a formation of very low altitude parasitic small satellites capturing the signal transmitted by existing LEO SARs in C and X bands. Both orbital analysis and radar performance estimation are performed. In order to increase the number of potential illuminators and achieve limited lifetimes, the receiver is supposed to be in a very LEO (alt...
Source: Advances in Space Research - Category: Science Source Type: research
The device — designed to be less invasive, more accurate and faster than existing tests for Lyme disease — could make it to market as early as the end of next year.
Source: Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
This article reviews bacterial, viral, fungal, and parasitic pathogens associated with myelopathy. Infectious myelopathies may be due to direct infection or parainfectious autoimmune-mediated mechanisms; this article focuses primarily on the former. RECENT FINDINGS Some microorganisms exhibit neurotropism for the spinal cord (eg, enteroviruses such as poliovirus and flaviviruses such as West Nile virus), while others are more protean in neurologic manifestations (eg, herpesviruses such as varicella-zoster virus), and others are only rarely reported to cause myelopathy (eg, certain fungal and parasitic infections). Indiv...
Source: CONTINUUM: Lifelong Learning in Neurology - Category: Neurology Tags: Review Articles Source Type: research
By Megan Molteni for WIRED. First comes the unscratchable itching, and the angry blossoming of hives. Then stomach cramping, and — for the unluckiest few — difficulty breathing, passing out, and even death. In the last decade and a half, thousands of previously protein-loving Americans have developed a dangerous allergy to meat. And they all have one thing in common: the lone star tick. Red meat, you might be surprised to know, isn’t totally sugar-free. It contains a few protein-linked saccharides, including one called galactose-alpha-1,3-galactose, or alpha-gal, for short. More and more people are lear...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Zika virus, Ebola, Middle East Respiratory Syndrome (MERS) coronavirus, Severe Acute Respiratory Syndrome (SARS) coronavirus, Nipah virus, Hendra virus, bird flu, swine flu -- these viruses have all grabbed international attention in recent years. In the past few decades the world has witnessed an alarming surge in emerging infectious diseases (EIDs). Since 1980, new pathogens have emerged in the human population at a rate of about three each year. Why are we seeing such a surge in new pathogens? One could argue that some of the pathogens may not be new at all; they could have circulated among humans for centuries and are...
Source: Science - The Huffington Post - Category: Science Source Type: news
Conclusion Overall, this review provides insights into how climate change might lead to the transmission of tropical diseases in what are currently temperate parts of the world, such as the UK. Predicting what may happen in the future can help countries make sure they are prepared for such an eventuality. This review was informed by a search for relevant literature, but may not have captured or included all relevant studies. Most of the studies were modelling studies, which are reliant on various assumptions that may or may not turn out to be correct. It's not possible to say with any certainty what will occur in the fut...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice QA articles Source Type: news
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