Development and Application of Two Independent Real-time PCR Assays to Detect Clinically Relevant Mucorales Species.

In conclusion, combination of the two independent Mucorales assays described in this study, 18S and 28S, detected all clinical samples associated with proven Mucorales infection (n=10). Reliable and specific identification of Mucorales is a prerequisite for successful antifungal therapy as these fungi show intrinsic resistance to voriconazole and caspofungin. PMID: 26743820 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26743820?dopt=Abstract

Source: Journal of Medical Microbiology - January 7, 2016 Category: Microbiology Authors: Springer J, Goldenberger D, Schmidt F, Weisser M, Wehrle-Wieland E, Einsele H, Frei R, Loeffler J Tags: J Med Microbiol Source Type: research