Efficacy and safety of apixaban compared with aspirin in the elderly: a subgroup analysis from the AVERROES trial

Conclusions: older patients with AF are at particularly high risk of stroke if given aspirin and have substantially greater relative and absolute benefits from apixaban compared with younger patients with no greater risk of haemorrhage.
Clinical Trial Registration: ClinicalTrials.gov number: NCT00496769. URL: https://clinicaltrials.gov/ct2/show/NCT00496769.

Source: Age and Ageing - January 13, 2016 Category: Geriatrics Authors: Ng, K. H., Shestakovska, O., Connolly, S. J., Eikelboom, J. W., Avezum, A., Diaz, R., Lanas, F., Yusuf, S., Hart, R. G. Tags: Research Papers Source Type: research