β-Lapachone enhances Mre11-Rad50-Nbs1 complex expression in cisplatin-induced nephrotoxicity.

CONCLUSION: Although, it remains unclear how β-lapachone induces MRN complex expression, our findings suggest that β-lapachone might affect MRN complex expression and participate in DNA damage recovery in cisplatin-induced nephrotoxicity. PMID: 26721347 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/26721347?dopt=Abstract

Source: Pharmacological Reports - January 13, 2016 Category: Drugs & Pharmacology Authors: Kim TW, Kim YJ, Kim HT, Park SR, Jung JY Tags: Pharmacol Rep Source Type: research

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