Impact of high doses of 6% hydroxyethyl starch 130/0.42 and 4% gelatin on renal function in a pediatric animal model

ConclusionsAfter high doses of HES or GEL in piglets, no relevant impact on renal function could be found. These results confirm that AKI after HES or GEL is very unlikely in hemodynamically stable perioperative patients with normal renal function.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fpan.12834

Source: Pediatric Anesthesia - December 30, 2015 Category: Anesthesiology Authors: Lars Witt, Silke Glage, Ralf Lichtinghagen, Lars Pape, Dietmar Boethig, Nils Dennhardt, Sebastian Heiderich, Andreas Leffler, Robert Sümpelmann Tags: Original Article Source Type: research