Ganglioside GQ1b induces dopamine release through the activation of Pyk2

In conclusion, low concentration of GQ1b is able to enhance asynchronous DA release through Pyk2/ERK/Synapsin I/actin pathway. Our findings provide new insights into the role of GQ1b in neuronal communication, and implicate the potential application of GQ1b in neurological disorders.
Source: Molecular and Cellular Neuroscience - Category: Neuroscience Source Type: research