Alzheimer's disease or Alzheimer's syndrome?: a longitudinal computed tomography neuroradiological follow‐up study of 56 cases diagnosed clinically as Alzheimer's disease

ConclusionCases of so‐called Alzheimer's disease, as observed through continued clinical follow‐up and serial CT examinations, appear so diverse in symptomatology and radiological pathomorphology that it is difficult to consider them a single nosological entity. The pathology of Alzheimer's disease has to be reconsidered in accordance with the variety observed in the sequential development of neuroradiological findings. The pathology must be reconstructed in terms of topographical dimensions and chronological developments. The diagnosis of Alzheimer's disease appears to be not so simple based on any conventional diagnostic operational standards.

Source: Psychogeriatrics - December 16, 2015 Category: Geriatrics Authors: Kohshiro Fujisawa, Sadaharu Tsunoda, Hiroaki Hino, Katsuhiko Shibuya, Ayako Takeda, Naoya Aoki Tags: ORIGINAL ARTICLE Source Type: research