TET proteins help maintain genome integrity

(La Jolla Institute for Allergy and Immunology) Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news