Infertile worms resist infection-induced neurodegeneration

Intriguing exception to pattern of infection leading to neuro-disease.The connections are still obscure, but mounting evidence points to a link between infections, the immune system, and...
Source: Parkinson's Disease News From Medical News Today - Category: Neurology Tags: Alzheimer's / Dementia Source Type: news

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This has been developed to support leaders and managers working across health and social care to implement the learning outcomes of the Dementia Training Standards Framework, which ensures staff have the right knowledge and skills to deliver high quality, person-centred care.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Michaela D. Gjerstad, Guido Alves, Jodi Maple-Gr ødem
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Researchers from Georgetown University Medical Center in Washington DC have discovered blocking a certain protein in the brain can clear away nerve damaging build-ups.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Georgetown University Medical Center) A team of neurologists at Georgetown University Medical Center has found that inhibiting the USP13 molecule may be a therapeutic target in Parkinson's disease and other similar forms of neurodegeneration.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Porta M, Pilloni G, Pili R, Casula C, Murgia M, Cossu G, Pau M Abstract Background: Although physical activity (PA) is known to be beneficial in improving motor symptoms of people with Parkinson's disease (pwPD), little is known about the relationship between gait patterns and features of PA performed during daily life. Objective: To verify the existence of possible relationships between spatiotemporal and kinematic parameters of gait and amount/intensity of PA, both instrumentally assessed. Methods: Eighteen individuals affected by PD (10F and 8M, age 68.0 ± 10.8 years, 1.5 ≤ Hoehn and Yahr (H&Y)
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Scientists studying the tissue bequeathed to the Sydney Brain Bank hope it will lead them to an eventual cure for neurodegenerative diseasesIt ’s a rainy Wednesday morning and Dr Andrew Affleck is driving more carefully than usual on his way to the Neuroscience Research Australia building in Randwick.It ’s not just the slick, crowded roads putting the edge on his caution; in the boot of his car, cocooned in several layers of protective container and nestled in ice, is the brain of a human being who was alive only a few hours earlier.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Health Dementia Alzheimer's Australia news Parkinson's disease Sydney Science Source Type: news
In this study, BV2 microglial cells were stimulated with interferon-gamma and lipopolysaccharide and treated with GYY4137. The agent did not influence the viability of BV2 cells in concentrations up to 200 μM. It inhibited tumor necrosis factor but not interleukin-6 production. Expression of CD40 and CD86 were reduced under the influence of the donor. The phagocytic ability of BV2 cells and nitric oxide production were also affected by the agent. Surprisingly, GYY4137 upregulated generation of reactive oxygen species (ROS) by BV2 cells. The effect was mimicked by another H2S donor, Na2S, and it was not reproduced in...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
This article will discuss the current barriers to broader implementation of telemedicine for geriatric patients including reimbursement from the Medicare program. Medicare reimbursement for telemedicine is limited to rural areas, which does not allow for the widespread development of telemedicine programs. All Medicare beneficiaries would benefit from increased access to telemedicine services, not only those living in rural areas. As many elderly and disabled individuals have mobility problems, home-based telemedicine services should also be made available. There are efforts in Congress to expand the coverage of these serv...
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
DISCUSSION: The forms of tau in CSF and plasma are distinct, but in each specimen type, the levels of certain fragments are increased in AD. Measurement of plasma NT1 tau should be aggressively pursued as a potential blood-based screening test for AD/AD-MCI. PMID: 30419228 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
DISCUSSION: The following is a summary of the invited presentations and moderated discussions of both the review of scientific understanding and identification of gaps to inform further investigations. PMID: 30415806 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
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