Wegner's granulomatosis developing for the first time in a patient eight years after starting maintenance hemodialysis.

Wegner's granulomatosis developing for the first time in a patient eight years after starting maintenance hemodialysis.
Saudi J Kidney Dis Transpl. 2015 Nov-Dec;26(6):1262-1265
Authors: Ali AR, El-Reshaid K
Abstract
Wegener's granulomatosis is a serious autoimmune disorder characterized by necrotizing small-vessel vasculitis. It is a multisystem disease that primarily affects the lung and kidneys. Previous studies indicated few relapses of vasculitis after hemodialysis due to uremic immunosuppression. Our case report describes an end-stage renal failure patient who had developed non-caseating lung granulomata with giant cell formation and fibrinoid necrosis of arterial media that is consistent with Wegner's granulomatosis for the first time and eight years after initiation of maintenance hemodialysis. We believe that such a phenomenon has rarely been reported.
PMID: 26586069 [PubMed - as supplied by publisher]

Source: Saudi Journal of Kidney Diseases and Transplantation - November 1, 2015 Category: Urology & Nephrology Authors: Ali AR, El-Reshaid K Tags: Saudi J Kidney Dis Transpl Source Type: research