Cushing's syndrome: Genetic basis for cortisol excess

Cushing’s syndrome has been found to be linked to a genetic basis for cortisol excess. Cortisol is a hormone that is produced by the adrenal gland in response to stressful events, and modulates a whole spectrum of physiological processes. An international research collaboration has now identified genetic mutations that lead to the production and secretion of cortisol in the absence of an underlying stressor. This condition, known as Cushing's syndrome, can be successfully treated by surgical removal of the affected adrenal gland.
Source: ScienceDaily Headlines - Category: Science Source Type: news