Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer

Conclusion:
These studies have revealed a correlation between tumor recurrence and changes of stromal microenvironment accompanied by altered EGFR signaling.

Source: Breast Cancer Research - November 18, 2015 Category: Cancer & Oncology Authors: Xue HoldmanThomas WelteKimal RajapaksheAdam PondCristian CoarfaQianxing MoShixia HuangSusan HilsenbeckDean EdwardsXiang ZhangJeffrey Rosen Source Type: research