No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT

Conclusions:
Neither increased levels of EBV IgG antibodies, including against EBNA-1, nor elevated cotinine levels indicative of tobacco use, were associated with an increased risk of CIS conversion to MS, or MS activity or progression over a 5-year follow-up.

Source: Neurology - November 9, 2015 Category: Neurology Authors: Munger, K. L., Fitzgerald, K. C., Freedman, M. S., Hartung, H.-P., Miller, D. H., Montalban, X., Edan, G., Barkhof, F., Suarez, G., Radue, E.-W., Sandbrink, R., Kappos, L., Pohl, C., Ascherio, A. Tags: MRI, Clinical trials Observational study (Cohort, Case control), Multiple sclerosis ARTICLE Source Type: research