Abstract 122: Activation of Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) Enhances Cyclooxygenase 2 Expression via Promoter Antioxidant Response Element in Preglomerular Vascular Smooth Muscle Cells (PGVSMCs) [Session Title: Concurrent XVIII C: Oxidative Stress II]

In conclusion, these results show a novel role of Nrf2 in inducing COX2 expression through binding to promoter ARE in the absence of increased ROS in rat PGVSMCs.

Source: Hypertension - November 3, 2015 Category: Cardiology Authors: Luo, Z., Welch, W. J., Wilcox, C. S. Tags: Session Title: Concurrent XVIII C: Oxidative Stress II Source Type: research