Alternaria Induces Production of Thymic Stromal Lymphopoietin in Nasal Fibroblasts Through Toll-like Receptor 2.

CONCLUSIONS: The results of this study show that TSLP expression could be induced in nasal fibroblasts by exposure to Alternaria and that TLR2 may be involved in the process. The promotion of TSLP production in nasal fibroblasts by airborne fungi may facilitate the development or exacerbation of Th2-type nasal inflammation, especially in CRS with nasal polyps. PMID: 26540503 [PubMed]

http://www.ncbi.nlm.nih.gov/pubmed/26540503?dopt=Abstract

Source: Allergy, Asthma and Immunology Research - November 7, 2015 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research