Cinnamaldehyde inhibits inflammation and brain damage in a mouse model of permanent cerebral ischaemia
Conclusions and ImplicationsCinnamaldehyde protects against cerebral ischaemia injury by inhibiting inflammation, partly mediated by reducing the expression of toll‐like receptor 4, tumour necrosis receptor‐associated factor 6 and the nuclear translocation of NF‐κB. Our findings suggest that cinnamaldehyde may serve as a new candidate for further development as a treatment for stroke.
Source: British Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Jingru Zhao, Xiangjian Zhang, Lipeng Dong, Ya Wen, Xiufen Zheng, Cong Zhang, Rong Chen, Ye Zhang, Yaoru Li, Tingting He, Xingyuan Zhu, Litao Li Tags: RESEARCH PAPER Source Type: research
More News: Brain | Drugs & Pharmacology | Ischemic Stroke | Neurology | Stroke | Study | Translocation