IQGAP1 Negatively Regulates Human Bladder Tumor Growth

This study used gene mutation information from patient-derived bladder tumor specimens to inform the development of a screen used to identify novel tumor growth suppressors. This included identification of the protein IQGAP1 as a potent bladder cancer growth suppressor. Mol Cancer Res; 13(9); 1306–15. ©2015 AACR.

Source: Molecular Cancer Research - September 13, 2015 Category: Cancer & Oncology Authors: Hensel, J., Duex, J. E., Owens, C., Dancik, G. M., Edwards, M. G., Frierson, H. F., Theodorescu, D. Tags: Genomics Source Type: research