Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model

CONCLUSION AND IMPLICATIONSChanges in GSK3β‐Ser9 phosphorylation in in vivo haemorrhagic shock models can be modelled in vitro, and this has identified a role for PPARγ activation in the protective role of VPA.

Source: British Journal of Pharmacology - September 1, 2015 Category: Drugs & Pharmacology Authors: Alexandra M E Zuckermann, Roberto M La Ragione, Deborah L Baines, Robin S B Williams Tags: RESEARCH PAPER Source Type: research