Effects of glucose‐lowering and multifactorial interventions on cardiovascular and mortality outcomes: a meta‐analysis of randomized control trials

ConclusionsApart from non‐fatal MIs, there was no evidence that intensive glucose‐lowering and multifactorial interventions reduced or increased the risk of cardiovascular and mortality outcomes. Intensive glucose‐lowering and multifactorial interventions are likely to be beneficial in populations with a higher baseline incidence of CV mortality, but there was no evidence of an association with the mean duration of Type 2 diabetes. Multifactorial interventions had a much greater impact on non‐fatal MI and non‐fatal strokes. (PROSPERO registration no.: 42014013860)This article is protected by copyright. All rights reserved.

Source: Diabetic Medicine - August 18, 2015 Category: Endocrinology Authors: S. Seidu, F. A. Achana, L. J. Gray, M. J. Davies, K. Khunti Tags: Systematic Review or Meta‐analysis Source Type: research